Journal
TETRAHEDRON LETTERS
Volume 51, Issue 45, Pages 5930-5932Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2010.09.024
Keywords
-
Categories
Funding
- EPSRC
- BBSRC
- GlaxoSmithKline
- Cambridge Trust
- Augustus Newman Foundation
Ask authors/readers for more resources
A tetrafluorophenol acrylamide monomer unit was synthesised, co-polymerised and grafted onto a glass slide to form individual gel spots. As a proof of principle study, a small library of amides was rapidly synthesised within these gel spots using 'catch-and-release' chemistry, including the biologically interesting quorum sensing acyl-homoserine lactones. The tetrafluorophenol acrylamide gel provides an efficient platform to synthesise and screen small molecules for biological activity. (C) 2010 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available