4.4 Article

KHSO4-mediated synthesis of α-amino phosphonates under a neat condition and their 31P NMR chemical shift assignments

Journal

TETRAHEDRON LETTERS
Volume 51, Issue 43, Pages 5708-5712

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2010.08.066

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Funding

  1. Council of Scientific and Industrial Research, New Delhi, India

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A simple and efficient method for the synthesis of a-amino phosphonates has been accomplished from aromatic aldehydes, diethyl phosphite, and aromatic (or) aliphatic amines using potassium hydrogen sulfate as a catalyst under solvent free condition at ambient temperature and these compounds are characterized by P-31 NMR with reference to H3PO4. (C) 2010 Elsevier Ltd. All rights reserved.

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