Journal
TETRAHEDRON LETTERS
Volume 51, Issue 2, Pages 371-373Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.11.023
Keywords
Amides; Halides; Amines; Palladium-catalysed carbonylation
Categories
Funding
- MIUR
- University of Salento
- C.I.N.M.P.I.S. (Consorzio Interuniversitario Nazionale Metodologie e Processi Innovativi di Sintesi)
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Amides can be prepared from allyl or benzyl halides and primary or secondary amines, using Pd(O) catalyst under CO pressure, in a one-pot synthesis. The reaction proceeds through the acyl palladium halide formation which undergoes an acylic nucleophilic substitution from the amine. (C) 2009 Elsevier Ltd. All rights reserved.
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