4.4 Article

Highly enantioselective synthesis of 3-cycloalkanone-3-hydroxy-2-oxindoles, potential anticonvulsants

Journal

TETRAHEDRON LETTERS
Volume 51, Issue 16, Pages 2157-2159

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2010.02.082

Keywords

Aldol Reaction; Aqueous medium; Organocatalyst; Enantioselective reaction; Anticonvulsants

Funding

  1. Department of Science & Technology, Govt. of India
  2. Council of Scientific & Industrial Research, Govt. of India

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Highly enantioselective catalytic synthesis of 3-cycloalkanone-3-hydroxy-2-oxindoles was achieved by using primary-tertiary diamine-Bronsted acid catalyst in both organic medium and aqueous medium. The products, thus obtained act as potential anticonvulsants. (c) 2010 Elsevier Ltd. All rights reserved.

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