4.4 Article

Gold-catalyzed C-S bond formation from thiols

Journal

TETRAHEDRON LETTERS
Volume 51, Issue 2, Pages 378-381

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.11.025

Keywords

Gold catalysis; Substitution; Sulfide

Funding

  1. Universite de Rennes 1
  2. Region Bretagne and Rennes Metropole

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ortho-Alkynylbenzoic acid alkyl esters act as alkylating agents of thiol derivatives with PPh3AuCl in combination with AgOTf in 1,2-dichloroethane at 80 degrees C. The corresponding sulfide compounds are obtained in good to excellent yields. (C) 2009 Elsevier Ltd. All rights reserved.

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