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Diastereoselective synthesis of spiro-functionalized tetraalkyl benzoisoquinopyrrolonaphthyridine-tetracarboxylates from isoquinoline, dialkyl acetylenedicarboxylates, and indane-1,3-dione

TETRAHEDRON LETTERS (2010)

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Journal

TETRAHEDRON LETTERS
Volume 51, Issue 2, Pages 396-398

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.11.040

Keywords

Isoquinoline; Tandem reaction; Acetylenic esters; Spiro compound; Indane-1,3-dione

Categories

Chemistry, Organic

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An effective route to spiro-functionalized fused polycyclic derivatives of isoquinoline is described via tandem reaction of isoquinoline, dialkyl acetylenedicarboxylates, and indane-1,3-dione. (C) 2009 Elsevier Ltd. All rights reserved.

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