Journal
TETRAHEDRON LETTERS
Volume 51, Issue 48, Pages 6301-6304Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2010.09.107
Keywords
2-Hydroxyethylcarbamates, 1,3-Disubstituted ureas; Organic catalysis; Solventless reaction
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A new solventless method for the synthesis of symmetrical and unsymmetrical ureas, starting from ethylene carbonate and amines, is reported. 1,5,7-Triazabicyclo[4.4.0]dec-5-ene(TBD) and thioureas have been found to be efficient organocatalysts for this reaction. (C) 2010 Elsevier Ltd. All rights reserved.
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