4.4 Article

One-pot synthesis of phthalides via regioselective intramolecular cyclization from ortho-alkynylbenzaldehydes

Journal

TETRAHEDRON LETTERS
Volume 51, Issue 45, Pages 5937-5939

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2010.09.023

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A one-pot synthesis of phthalides via an intramolecular 5-exo-dig cyclization of ortho-alkynylbenzaldehydes under mild NaClO2 oxidation conditions is described. (C) 2010 Elsevier Ltd. All rights reserved.

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