Journal
TETRAHEDRON LETTERS
Volume 51, Issue 7, Pages 1030-1033Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.12.070
Keywords
Cyclization; Oximes; Copper
Categories
Funding
- Orionpharma Corporation
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A practical and effective room temperature copper-catalyzed cyclization of Z-oximes is developed. 3-Methyl-1,2-benzisoxazoles are obtained in 58-79% yields, Also, the Z-selective synthesis of o-bromo acetophenone oximes is presented for the first time. (C) 2009 Elsevier Ltd. All rights reserved.
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