4.4 Article

Site-selective Suzuki cross-coupling reactions of 2,3-dibromobenzofuran

Journal

TETRAHEDRON LETTERS
Volume 51, Issue 18, Pages 2420-2422

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2010.02.141

Keywords

Catalysis; Palladium; Suzuki-Miyaura reaction; Site-selectivity; Benzofuran

Funding

  1. State of Pakistan (HEC)
  2. DAAD
  3. State of Vietnam (MOET)
  4. State of Mecklenburg-Vorpommern

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The Suzuki-Miyaura reaction of 2,3-dibromobenzofuran with two equivalents of boronic acids gave 2,3-diarylbenzofurans. The reaction with one equivalent of arylboronic acids resulted in site-selective formation of 2-aryl-3-bromobenzofurans. 2,3-Diarylbenzofurans containing two different aryl groups were prepared from 2,3-dibromobenzofuran in a one-pot protocol by sequential addition of two different boronic acids. (C) 2010 Elsevier Ltd. All rights reserved.

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