Journal
TETRAHEDRON LETTERS
Volume 51, Issue 30, Pages 3944-3950Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2010.05.102
Keywords
Mercaptopropylsilica (MPS); Heterogeneous catalyst; Recyclable; Room temperature; 2,4,5-Tri- and 1,2,4,5-tetrasubstituted imidazoles; Aqueous methanol; Bis-imidazoles; Trifenagrel
Categories
Funding
- University Grants Commission, New Delhi
- UGC [F. 37-398/2009]
Ask authors/readers for more resources
The heterogeneous solid catalyst, mercaptopropylsilica (MPS), has been prepared by a modified procedure in water and its structure confirmed by solid state carbon-13 CP-MAS NMR spectrum. This catalyst has been efficiently utilized for the synthesis of a wide variety of tri-, tetrasubstituted imidazoles and their bis-analogues at room temperature. The protocol was further explored for the synthesis of the drug trifenagrel. (C) 2010 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available