4.4 Article

Total synthesis of (+)-aspermytin A

Journal

TETRAHEDRON LETTERS
Volume 51, Issue 30, Pages 3966-3968

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2010.05.107

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Funding

  1. Program for Promotion of Basic and Applied Research for Innovations in the Bio-oriented Industry (BRAIN)

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The first enantioselective total synthesis of aspermytin A, a new neurotrophic polyketide isolated from a cultured marine fungus of the genus Aspergillus sp., has been accomplished in 24 steps with an overall yield of 9.7% from S-(-)-citronellal. (C) 2010 Elsevier Ltd. All rights reserved.

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