Journal
TETRAHEDRON LETTERS
Volume 51, Issue 5, Pages 790-792Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.11.100
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Funding
- Council of Sharif University of Technology
- Faculty of Chemistry of Tarbiat Moallem University
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A new and facile protocol for the synthesis of 2-amino-1,3,4-thiadiazoles in water is described. Reaction of acid hydrazides with easily prepared dithiocarbamates gives the corresponding thiadiazoles in moderate to excellent yields. 2-Amino-1,3,4-oxadiazoles were not observed as side products using this procedure. (c) 2009 Elsevier Ltd. All rights reserved.
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