4.4 Article

Oxidative dimerization of azoles via copper(II)/silver(I)-catalyzed CH homocoupling

Journal

TETRAHEDRON LETTERS
Volume 51, Issue 5, Pages 850-852

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.12.016

Keywords

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Funding

  1. Grant-in-Aid for Scientific Research on Priority Areas, 'Advanced Molecular Transformation of Carbon Resources'
  2. Special Coordination Funds for Promoting Science and Technology, Creation of innovation Centers for Advanced Interdisciplinary Research Areas (Innovative Bioproduction Kobe)
  3. Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan

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When several azole derivatives such as imidazole, thiazole, and oxazole are treated with a catalyst system of copper(II)/silver(I) under oxygen atmosphere, oxidative dimerization at the CH bond of the 2-position takes place to afford the corresponding bisazoles up to 86% yield. (c) 2009 Elsevier Ltd. All rights reserved.

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