Journal
TETRAHEDRON LETTERS
Volume 51, Issue 44, Pages 5764-5766Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2010.08.027
Keywords
Soft coral; Sinularia flexibilis; Thioflexibilolide A; Anti-inflammatory activity; Neuroprotective activity
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Funding
- National Science Council [NSC-98-2113-M-110-002-MY3]
- Ministry of Education of Taiwan [98C031702]
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A structurally unique symmetric sulfur-containing biscembranoid, namely, thioflexibilolide A (1), was isolated from the soft coral Sinularia flexibilis. The structure was determined by extensive spectroscopic analyses. Compound 1 has been found to possess significant anti-inflammatory and neuroprotective activities. (C) 2010 Elsevier Ltd. All rights reserved.
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