4.4 Article

Chemoselective sulfide oxidation mediated by bridged flavinium organocatalysts

Journal

TETRAHEDRON LETTERS
Volume 51, Issue 17, Pages 2362-2365

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2010.02.164

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Funding

  1. Leverhulme Trust
  2. Astra Zeneca

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The chemoselective oxidation of sulfides to sulfoxides, catalysed by bridged, tetracyclic flavinium catalysts is presented. The flavinium catalysts are easily prepared via a telescoped three-step process. A range of sulfoxides is accessed in excellent yield and chemoselectivity. (C) 2010 Elsevier Ltd. All rights reserved.

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