Journal
TETRAHEDRON LETTERS
Volume 51, Issue 27, Pages 3571-3574Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2010.05.003
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Funding
- Natural Science Foundation of Shanghai [08ZR1405900]
- Shanghai Committee of Science and Technology [09JC1404500]
- '111' Project [B07023]
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A new NHCs-mediated synthetic method was found to produce alpha-aryl ketones in 22-63% yields in one-pot process from the corresponding aromatic aldehydes and benzyl halides. This method is the first example of the NHCs-mediated intermolecular nucleophilic acylation of aromatic aldehydes with benzyl halides. (C) 2010 Elsevier Ltd. All rights reserved.
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