Journal
TETRAHEDRON LETTERS
Volume 51, Issue 25, Pages 3334-3336Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2010.04.086
Keywords
Indoles; Regioselective cyanation; Pd(OAc)(2); 3-Cyanoindoles; C-H activation
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Funding
- CSIR, New Delhi
- UGC, New Delhi
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Indoles undergo smooth cyanation with CuCN in the presence of 20 mol% Pd(OAc)(2) and 40 mol% CuBr2 in DMF to produce a wide range of the corresponding 3-cyanoindoles in good yields with high regioselectivity. (C) 2010 Elsevier Ltd. All rights reserved.
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