Journal
TETRAHEDRON LETTERS
Volume 51, Issue 6, Pages 959-960Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.12.041
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Funding
- Ministry of Education, Culture, Sports, Science and Technology, Japan
- Keio Gijuku Academic Development Funds
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A 14-membered macrolide, koshikalide (1), was isolated from the marine cyanobacterium Lyngbya sp., and its planar structure was elucidated by spectroscopic analysis. The relative stereochemistry of C-I I and C-13 was elucidated by NOESY experiments and by an analysis of H-1-H-1 coupling constants. Koshikalide (1) exhibited weak cytotoxicity against HeLa S-3 cells. (C) 2009 Elsevier Ltd. All rights reserved.
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