4.4 Article

Enantioselective epoxidation of 2-substituted 1,4-naphthoquinones using gem-dihydroperoxides

Journal

TETRAHEDRON LETTERS
Volume 50, Issue 32, Pages 4629-4632

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.05.096

Keywords

gem-Dihydroperoxides; Enantioselective epoxidation; 1,4-Naphthoquinones; Thujone; Epoxides

Funding

  1. DFG

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New gem-dihydroperoxides were successfully used for DBU-promoted enantioselective epoxidation of 2-substituted 1,4-naphtlloquinones. The corresponding 1,4-naphthoquinone epoxides were obtained in yields up to 97% and ee's up to 82%. (C) 2009 Elsevier Ltd. All rights reserved.

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