4.4 Article

FeCl3-catalyzed Ritter reaction. Synthesis of amides

Journal

TETRAHEDRON LETTERS
Volume 50, Issue 26, Pages 3470-3473

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.02.208

Keywords

Ritter reaction; Nitriles; Amides; Iron

Funding

  1. CNRS

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A safe and inexpensive synthesis of amides, from benzylic alcohols and nitriles and from t-butyl acetate and nitriles, using a Ritter reaction catalyzed by FeCl3 center dot 6H(2)O is described. (C) 2009 Elsevier Ltd. All rights reserved.

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