Journal
TETRAHEDRON LETTERS
Volume 50, Issue 26, Pages 3602-3605Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.03.086
Keywords
Multicomponent reaction; Oxindole; Palladium; C-H activation; N-Arylation; Carbopalladation
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Funding
- CNRS
- Ministere de l'Enseignement Superieur et de la Recherche
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A palladium-catalyzed three-component synthesis of 3-(diarylmethylene)indolin-2-ones has been developed. A sequence of intermolecular N-arylation/intermolecular carbopalladation/C-H activation/C-C bond formation was realized in a one-pot fashion allowing the construction of one C-N bond and two C-C bonds by way of three distinct catalytic cycles. (C) 2009 Elsevier Ltd. All rights reserved.
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