4.4 Article

'On water': unprecedented nucleophilic substitution and addition reactions with 1,4-quinones in aqueous suspension

Journal

TETRAHEDRON LETTERS
Volume 50, Issue 43, Pages 5896-5902

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.07.149

Keywords

Quinone; Naphthoquinones; Water; Green synthesis; Amines; Thiols; Amino acids

Funding

  1. UGC, New Delhi, India

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Unique nucleophilic substitution and addition reactions of 1,4-quinones in aqueous suspension with aromatic amines, primary aliphatic amines, amino acid, ester of amino acid, heterocyclic amines, hydrazine, amide, and thioethers are described in absence of catalyst against the traditional synthetic routes of these reactions in non-aqueous medium in presence of catalyst. (C) 2009 Elsevier Ltd. All rights reserved.

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