4.4 Article

A novel three-component reaction for the synthesis of N-cyclohexyl-3-aryl-quinoxaline-2-amines

Journal

TETRAHEDRON LETTERS
Volume 50, Issue 7, Pages 767-769

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2008.11.123

Keywords

O-Phenylenediamine; N-Cyclohexyl-3-aryl-quinoxaline-2-amines; Ferric perchlorate; Cyclohexyl isocyanide; Three-component reactions

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Ferric perchlorate catalyzes the three-component condensation reaction of o-phenylenediamine, aromatic alclehydes, and cyclohexyl isocyanide to afford the corresponding N-cyclohexyl-3-aryl-quinoxaline-2-amines in good yields. (C) 2008 Elsevier Ltd. All rights reserved.

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