Journal
TETRAHEDRON LETTERS
Volume 50, Issue 28, Pages 4101-4103Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.04.101
Keywords
Click chemistry; Artificial oligonucleotide; Convergent synthesis; Solution-phase synthesis
Categories
Funding
- KAKENHI [20655026/20108015]
- Dean's Grant for Exploratory Research
Ask authors/readers for more resources
A convergent route for the solution-phase synthesis of oligomeric triazole-linked analogues of DNA ((TL)DNA) has been developed. A one-pot procedure for desilylation of masked acetylene and the ensuing copper-catalyzed Huisgen coupling reaction between oligomers allowed the solution-phase synthesis of 7-mer and 8-mer (TL)DNA in good yield. (C) 2009 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
