4.4 Article

A microfluidic flow chemistry platform for organic synthesis: the Hofmann rearrangement

Journal

TETRAHEDRON LETTERS
Volume 50, Issue 26, Pages 3287-3289

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.02.059

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Funding

  1. EPRSC
  2. University of Camerino
  3. MIUR-Italy
  4. CSIRO
  5. Advion Flow Research Fellowship

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We report on the use of commercially available chemical microreactors to effect the Hofmann rearrangement of aromatic amides to the corresponding carbamates. Crown Copyright (C) 2009 Published by Elsevier Ltd. All rights reserved.

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