A one-pot synthetic approach to the functionalized isomeric ellipticine derivatives through an imino Diels-Alder reaction

An efficient, three component, one-pot synthesis of new isomeric ellipticine derivatives prepared through all imino Diels-Alder reaction of 3-aminocarbamles and substituted benzaldehydes with electron-rich alkenes such as 3,4-dihydro-2H-pyran, 2,3-dihydrofuran and ethyl vinyl ether catalyzed by InCl3 (10 mol %) in ionic liquid is reported. In the Case Of Substituted benzaldehydes, reductive amination is observed. (C) 2009 Published by Elsevier Ltd.