Journal
TETRAHEDRON LETTERS
Volume 50, Issue 37, Pages 5248-5250Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.07.018
Keywords
Hantzsch reaction; 1,4-Dihydropyridines; Triphenylphosphine; One-step condensation
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An efficient one-step synthesis of 1,4-dihydropyridines in good to excellent yields via the triphenylphosphine-catalyzed Hantzsch three-component reaction of an aromatic aldehyde, ethyl acetoacetate and ammonium acetate is described. (C) 2009 Elsevier Ltd. All rights reserved.
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