Journal
TETRAHEDRON LETTERS
Volume 50, Issue 45, Pages 6166-6168Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.08.079
Keywords
-
Categories
Funding
- Shenogen Pharma Group
Ask authors/readers for more resources
A short and highly enantioselective synthesis of both enantiomers of GABA agonist baclofen in four steps with total yields of 32.8% [for(S)-isomer] and 35.1% [for (R)-isomer] is reported. The key step involved desymmetrization of cyclic anhydride with modified cinchona alkaloids. (C) 2009 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available