4.4 Article

Lewis acid-catalyzed reactions of N′-(2-alkynylbenzylidene)hydrazides with diethyl phosphite

Journal

TETRAHEDRON LETTERS
Volume 50, Issue 29, Pages 4279-4282

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.05.013

Keywords

N '-(2-Alkynylbenzylidene)hydrazide; Copper triflate; Diethyl phosphite; Palladium acetate

Funding

  1. National Natural Science Foundation of China [20772018]
  2. Shanghai Pujiang Program, and Program for New Century Excellent Talents in University [NCET-07-0208]

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Lewis acid catalyst-tuned reactions of N'-(2-alkynylbenzylidene)hydrazides with diethyl phosphite are described. Isoquinolin-1-ylphosphonate is generated when copper triflate is utilized as catalyst, while 2-amino-1,2-dihydroisoquinolin-1-ylphosphonate is obtained in the presence of palladium acetate. (C) 2009 Elsevier Ltd. All rights reserved.

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