Journal
TETRAHEDRON LETTERS
Volume 50, Issue 25, Pages 2998-3000Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.03.188
Keywords
Arylidene Meldrum's acids; Michael reaction; Trifluoromethylation
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Funding
- Russian Academy of Sciences
- Ministry of Science, Russian Foundation for Basic Research [08-03-00428]
- Russian Science Support Foundation
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A method for the trifluoromethylation of arylidene Meldrum's acids using Me3SiCF3 followed by transformation of the initial products to CF3-substituted esters and alcohols is described. The sequence of reactions is performed without isolation of intermediate compounds furnishing the final products in good overall yields. (C) 2009 Elsevier Ltd. All rights reserved.
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