4.4 Article

An efficient metal-free reduction using diphenylsilane with (tris-perfluorophenyl)borane as catalyst

Journal

TETRAHEDRON LETTERS
Volume 50, Issue 34, Pages 4912-4915

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.06.066

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Funding

  1. Institute of Bioengineering and Nanotechnology (Biomedical Research Council, Agency for Science, Technology and Research, Singapore)

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An efficient metal-free reduction of various C=X (X = O, N, C) bonds into their corresponding amines or hydrocarbons using the Ph2SiH2/B(C6F5)(3) catalytic system is demonstrated. This protocol reduces enamines, enol esters, carbonyls, amides, and isocyanates. (C) 2009 Elsevier Ltd. All rights reserved.

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