Journal
TETRAHEDRON LETTERS
Volume 50, Issue 25, Pages 3050-3053Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.04.029
Keywords
Horner-Wadsworth-Emmons reaction; Isoindolinones; Cyclisation; Heterogeneous catalysis; Enones
Categories
Funding
- CAM [S-0505/PPQ/0344]
- MEC (Spanish Ministry of Education and Science) [MEC FPU AP2005-5112]
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An intramolecular Horner-Wadsworth-Emmons reaction promoted by KF-Alumina involving a N-substituted phthalimide, cleanly and efficiently furnishes an interesting alpha,beta-unsaturated tricyclic enone which may undergo selective alkylations at the alpha'-position. (C) 2009 Elsevier Ltd. All rights reserved.
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