4.4 Article

Efficient synthesis of indenes by FeCl3•6H2O-catalyzed intramolecular Friedel-Crafts reaction of aryl-substituted allylic alcohols

Journal

TETRAHEDRON LETTERS
Volume 50, Issue 35, Pages 4978-4982

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.06.070

Keywords

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Funding

  1. NNSF of China, 973 program [2009CB825300]
  2. NSF of Shanghai
  3. Shanghai Leading Academic Discipline Project [13108]

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An efficient procedure for the synthesis of substituted indenes through the FeCl3 center dot 6H(2)O-catalyzed intramolecular Friedel-Crafts cyclization of aryl-substituted allylic alcohols has been developed. This method features the easily available starting materials, cheap catalyst, simple manipulation, and mild conditions. (C) 2009 Elsevier Ltd. All rights reserved.

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