4.4 Article

Synthesis of functionalized benzothiophenes by twofold Heck and subsequent 6π-electrocyclization reactions of 2,3-dibromothiophene

Journal

TETRAHEDRON LETTERS
Volume 50, Issue 35, Pages 4962-4964

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.06.057

Keywords

Thiophenes; Catalysis; Domino reactions; Sulfur heterocycles; Palladium

Funding

  1. DAAD
  2. State of Pakistan
  3. State of Mecklenburg-Vorpommern

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The Heck reaction of 2,3-dibromothiophene afforded 2,3-di(alkenyl)thiophenes which were transformed into benzothiophenes by domino '6 pi-electrocyclization/dehydrogenation' reactions. (C) 2009 Elsevier Ltd. All rights reserved.

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