4.4 Article

Pd(0)-catalyzed intramolecular Heck reaction: a versatile route for the synthesis of dibenzoazocinone derivatives

Journal

TETRAHEDRON LETTERS
Volume 50, Issue 34, Pages 4866-4869

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.06.030

Keywords

Heck reaction; Palladium catalyst; Benzoazocinone; 8-Exo-trig; Aza-Claisen rearrangement

Funding

  1. CSIR (New Delhi)
  2. DST (New Delhi)

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Two efficacious synthetic methodologies for the construction of medium-sized nitrogen heterocycles dibenzoazocinones have been developed. The phosphine-assisted protocol afforded better yields of the dibenzoazocinones (73-82%). (c) 2009 Elsevier Ltd. All rights reserved.

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