4.4 Article

Coupling reactions of hindered isonitriles and hindered alkyl thioacids: mechanistic studies

Journal

TETRAHEDRON LETTERS
Volume 50, Issue 36, Pages 5152-5155

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.06.129

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Funding

  1. NIH [CA103823]

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The coupling reaction between hindered thioacids and isonitriles is developed and described. The mechanism for the formation of the thiopyruvamide products is explored, and the method is applied to a selection of substrates. (C) 2009 Elsevier Ltd. All rights reserved.

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