4.4 Article

A simple and expedient method for the preparation of N-chlorohydantoins

Journal

TETRAHEDRON LETTERS
Volume 50, Issue 6, Pages 656-658

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2008.11.091

Keywords

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Funding

  1. NIH [R01-GM082961]
  2. ACS-PRF [47272-AC]

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A simple and efficient methodology for the preparation of N-chlorinated hydantoins is presented. These versatile chlorenium sources were isolated in high yield after a simple recrystaillization. Among the ten examples are the first chiral N-chlorohydantoins. (C) 2008 Elsevier Ltd. All rights reserved.

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