Journal
TETRAHEDRON LETTERS
Volume 50, Issue 26, Pages 3158-3160Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2008.12.086
Keywords
Bidentate phosphoramidite ligand; Rhodium catalyst; Asymmetric hydrogenation
Categories
Funding
- Grant-in-Aid for Scientific Research in Priority Areas [18064001]
- Ministry of Education, Culture, Sports, Science, and Technology, Japan [B01]
- Grants-in-Aid for Scientific Research [18064001] Funding Source: KAKEN
Ask authors/readers for more resources
High performance of Me-BIPAM for enantioselective hydrogenation of alpha-dehydroamino esters, enamides, and dimethyl itaconate was demonstrated. [Rh(Me-BIPAM)(diene)]X (diene = cod, nbd; X = BF4, PF6, SbF6) gave optically active beta-aryl alpha-amino esters up to 99% ee, 1-arylethylamines up to 97% ee, methyl 2-acetylaminobutanoate with 90% ee, and dimethyl 2-methylsuccinate with 97% ee under 0.3-0.8 MPa dihydrogen with 0.1-1 mol% catalyst loading. (C) 2009 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
