4.4 Article

A one-pot, four-component synthesis of α-carboline derivatives

Journal

TETRAHEDRON LETTERS
Volume 50, Issue 52, Pages 7379-7381

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.10.077

Keywords

Indolin-2-one; Aldehyde; Pyrazole; Indolopyrazolopyridine; Carboline

Funding

  1. Research Council of Shahid Beheshti University

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A one-pot method for the efficient and simple synthesis of novel 1H-indolo[2,3-b]pyrazolo(4,3-e)pyridines via a four-component condensation reaction of indolin-2-one, 3-oxo-3-phenylpropanenitrile, and various hydrazines and aldehydes in the ionic liquid 1-butyl-3-methylimidazolium bromide ([bmim]Br) is reported. (C) 2009 Elsevier Ltd. All rights reserved.

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