4.4 Article

Formal [4+2] cycloaddition between 3-ethoxycyclobutanones and silyl enol ethers

Journal

TETRAHEDRON LETTERS
Volume 50, Issue 42, Pages 5831-5833

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.08.013

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Funding

  1. SUBOR
  2. Ministry of Education, Culture, Sports, Science, and Technology of Japan
  3. Grants-in-Aid for Scientific Research [21689001] Funding Source: KAKEN

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3-Ethoxycyclobutanones reacted with silyl enol ethers to give formal [4+2] cycloadducts, 3-ethoxy-5-trimethylsiloxycyclohexanone derivatives, by using ethylaluminum dichioride as a Lewis acid. Highly oxygenated cyclohexanone derivatives were stereoselectively prepared by this method. (C) 2009 Elsevier Ltd. All rights reserved.

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