4.4 Article

Indium-mediated double Barbier reaction of γ-cyanoesters derived from Baylis-Hillman adduct

Journal

TETRAHEDRON LETTERS
Volume 50, Issue 15, Pages 1696-1698

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.01.149

Keywords

Indium; Barbier reaction; Lactam; Baylis-Hillman adducts

Funding

  1. Korean Government (MOEHRD) [KRF-2008-313-C00487]

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We developed an efficient synthetic method of diallylated delta-valerolactam and gamma-butyrolactam derivatives via an indium-mediated successive double Barbier type allylations starting from the Baylis-Hillman adducts. (C) 2009 Elsevier Ltd. All rights reserved.

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