Journal
TETRAHEDRON LETTERS
Volume 50, Issue 17, Pages 2017-2018Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.02.100
Keywords
Lipases; Michael additions; Enzyme promiscuity; Catalysis
Categories
Funding
- CNPq
- CAPES
- FAPERJ
- FINEP
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The present Letter details our findings on the lipase-catalyzed Michael reactions between primary or secondary amines and acrylonitrile. Several lipases were evaluated, and good results were obtained leading to the formation of Michael adducts in shorter reaction times than the uncatalyzed reactions. (C) 2009 Elsevier Ltd. All rights reserved.
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