4.4 Article

An efficient and stereoselective route to 1-deoxy-5-hydroxy sphingosine analogues

Journal

TETRAHEDRON LETTERS
Volume 50, Issue 12, Pages 1328-1330

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.01.024

Keywords

Sphingolipids; Asymmetric synthesis; Asymmetric Henry reaction; Hydrolytic kinetic resolution; Regioselective ring opening

Funding

  1. CSIR
  2. UGC, New Delhi

Ask authors/readers for more resources

A short and efficient synthesis of 1-deoxy-5-hydroxy sphingolipid is described. The key steps involved are a Jacobsen hydrolytic kinetic resolution (HKR) and Shibasaki's asymmetric Henry reaction. (C) 2009 Elsevier Ltd. All rights reserved.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.4
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available