4.4 Article

Practical chemoenzymatic dynamic kinetic resolution of primary amines via transfer of a readily removable benzyloxycarbonyl group

Journal

TETRAHEDRON LETTERS
Volume 49, Issue 6, Pages 977-979

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2007.12.017

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A practical method for chemoenzymatic dynamic kinetic resolution of primary amines using dibenzyl carbonate as acyl donor has been developed leading to benzyl carbamates, which can be deprotected under very mild reaction conditions to give the free amine. (c) 2007 Elsevier Ltd. All rights reserved.

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