4.4 Article

The green and effective oxidation of alcohols to carboxylic acids with molecular oxygen via biocatalytic reaction

Journal

TETRAHEDRON LETTERS
Volume 49, Issue 7, Pages 1217-1219

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2007.12.032

Keywords

alcohol oxidation; molecular oxygen; biocatalyst; green chemistry; regeneration of cofactor

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A clean and effective alcohol oxidizing system using three enzymes has been developed. Regeneration of NAD(+) by NADH oxidase with molecular oxygen enabled to oxidize alcohols to carboxylic acids in good yield under mild conditions (25 degrees C, 1 atm). (c) 2007 Published by Elsevier Ltd.

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