Isothiouronium-based amphiphilic gold nanoparticles with a colorimetric response to hydrophobic anions in water: a new strategy for fluoride ion detection in the presence of a phenylboronic acid

Gold nanoparticles modified with isothiouronium-derived amphiphile units 1 were prepared by the reduction of AuCl4- (n-C8H17)(4)N+ with NaBH4 in the presence of bis(5-(N-(2-(2-methoxyethoxy)ethyl)-N-methyl-S-isothiouronio)pentyl) disulfide 2. The obtained rianoparticles 1 showed a selective coloration for hydrophobic anions in water, possibly due to an anion exchange and subsequent aggregation. Oil the basis of this observation, the detection of F- in water has been achieved using 3-nitrophenylboronic acid as a mediator at pH 5.5, thereby providing a new strategy for the design of a F- sensory system. (C) 2007 Elsevier Ltd. All rights reserved.