Journal
TETRAHEDRON LETTERS
Volume 49, Issue 41, Pages 5961-5964Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2008.07.151
Keywords
Sonogashira-Hagihara coupling; iron; copper; synergic effect
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Funding
- Swiss National Science Foundation (Bern)
- Roche Research Foundation (Basel)
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Synergic effect of iron and copper salts as catalysts for the Sonogashira-Hagihara cross-couplings of aryl iodides with terminal alkynes is demonstrated. High yields of cross-coupled products are obtained under conditions that are smoother than those using only Cul as catalyst. Furthermore no expensive or/and toxic ligand is required. (C) 2008 Elsevier Ltd. All rights reserved.
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