4.4 Article

Cycloaddition reactions of azomethine ylides with a 9-fluorenone-malononitrile Knoevenagel adduct

Journal

TETRAHEDRON LETTERS
Volume 49, Issue 41, Pages 5899-5901

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2008.07.127

Keywords

sarcosine; proline; azomethine ylide; cycloaddition

Funding

  1. University of Tehran

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Numerous derivatives of spiropyrrolidines and spiropyrrolizines containing cyano groups were Successfully synthesized via condensation of sarcosine and proline Schiff bases of several aromatic aldehydes with the Knoevenagel adduct of 9-fluorenone-malononitrile prepared through a modified procedure. Assignment of the molecular structure was carried Out by single crystal X-ray diffraction, as well as by HMBC and ROSEY spectroscopy. (C) 2008 Elsevier Ltd. All rights reserved.

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