4.4 Article

Synthesis of spirocyclopentene-indolines by intramolecular alkylidine insertion reactions

Journal

TETRAHEDRON LETTERS
Volume 49, Issue 38, Pages 5508-5510

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2008.07.043

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Funding

  1. Amgen Summer Internship program

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Intramolecular 1,5 CH insertion of unstabilized carbenes into the tertiary carbon of a substituted indoline generates spiro[cyclopent[2]ene-1,2'-indolines] in good yields and excellent enantioselectivities. (C) 2008 Elsevier Ltd. All rights reserved.

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